BCMA antibody (AA 78-184)
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- Target See all BCMA (TNFRSF17) Antibodies
- BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
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Binding Specificity
- AA 78-184
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This BCMA antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Coating (Coat), Staining Methods (StM)
- Purification
- Purified by Protein A/G
- Immunogen
- Recombinant human CD269 protein fragment (around aa 78-184) (exact sequence is proprietary)
- Clone
- BCMA-2366
- Isotype
- IgG2c kappa
- Top Product
- Discover our top product TNFRSF17 Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54) antibody
TNFRSF17 Reactivity: Human ELISA, FACS, IP, IF Host: Rabbit Monoclonal DM4 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) antibodyTNFRSF17 Reactivity: Human, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54) antibodyTNFRSF17 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 4D7E5 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-100) antibodyTNFRSF17 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 12-110) antibodyTNFRSF17 Reactivity: Human, Mouse WB, ELISA, FACS, IHC (p), IF (p), IHC (fro), IF (cc) Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54) antibodyTNFRSF17 Reactivity: Human WB, ELISA, FACS, IF Host: Mouse Monoclonal 10A9F7 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) antibodyTNFRSF17 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) antibodyTNFRSF17 Reactivity: Human WB, ELISA, FACS, IHC, ICC, Neut Host: Mouse Monoclonal 1D12G9 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-184) antibodyTNFRSF17 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3H6 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (Internal Region) antibodyTNFRSF17 Reactivity: Human WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
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Positive Control: NAMALWA cells. Tonsil or gastric carcinoma (IHC).
Known Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
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- Target
- BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
- Alternative Name
- CD269 (TNFRSF17 Products)
- Synonyms
- TNFRSF17 antibody, BCM antibody, BCMA antibody, CD269 antibody, TNFRSF13A antibody, Tnfrsf13 antibody, Tnfrsf13a antibody, TNF receptor superfamily member 17 antibody, tumor necrosis factor receptor superfamily, member 17 antibody, Tnfrsf17 antibody, TNFRSF17 antibody
- Background
- The B cell maturation protein (BCMA) is a type I integral membrane protein that belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is expressed as a 184 amino acid peptide that is expressed only in mature B-lymphocytes and is located on the cis part of the Golgi apparatus. BCMA shares significant homology with TACI (transmembrane activator) within the cysteine-rich domain. TACI has been shown to bind CAML, which induces activation of NFAT (nuclear factor of activated T cells). Both BCMA and TACI have been shown to bind APRIL and TALL-1, which stimulate B cell proliferation in conjunction with other B-cell activators. When overexpressed, TALL-1 stimulates the development of systemic lupus erythaematosus (SLE).
- Molecular Weight
- 20kDa
- Gene ID
- 608
- UniProt
- Q02223
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