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IL-1 beta antibody

IL1B Reactivity: Human WB, ELISA, IHC, ICC Host: Mouse Monoclonal 3A6 unconjugated
Catalog No. ABIN969215
  • Target See all IL-1 beta (IL1B) Antibodies
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    Reactivity
    • 122
    • 87
    • 43
    • 28
    • 24
    • 14
    • 8
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Host
    • 175
    • 63
    • 6
    • 6
    • 4
    • 2
    • 1
    Mouse
    Clonality
    • 181
    • 74
    • 1
    Monoclonal
    Conjugate
    • 135
    • 40
    • 23
    • 10
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This IL-1 beta antibody is un-conjugated
    Application
    • 183
    • 106
    • 89
    • 46
    • 43
    • 38
    • 28
    • 17
    • 17
    • 15
    • 14
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    • 10
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    • 3
    • 2
    • 1
    • 1
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    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human IL1B expressed in E. coli.
    Clone
    3A6
    Isotype
    IgG1
    Top Product
    Discover our top product IL1B Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Mohideen, Capili, Bilimoria, Yamada, Bonni, Lima: "A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 UBC9." in: Nature structural & molecular biology, Vol. 16, Issue 9, pp. 945-52, (2009) (PubMed).

    Kuo, Bentsi-Barnes, Barlow, Bae, Pisarska: "Sumoylation of forkhead L2 by Ubc9 is required for its activity as a transcriptional repressor of the Steroidogenic Acute Regulatory gene." in: Cellular signalling, Vol. 21, Issue 12, pp. 1935-44, (2009) (PubMed).

  • Target
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    Alternative Name
    IL1B (IL1B Products)
    Synonyms
    IL-1 antibody, IL1-BETA antibody, IL1F2 antibody, IL-1BETA antibody, IL1beta antibody, il1-b antibody, zgc:111873 antibody, IL-1B antibody, IL-1beta antibody, Il-1b antibody, IL1B antibody, IL-1 beta antibody, IL-1b antibody, interleukin 1 beta antibody, interleukin 1, beta antibody, IL1B antibody, il1b antibody, Il1b antibody
    Background

    Description: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.

    Aliases: IL-1, IL1F2, IL1-BETA

    Molecular Weight
    31 kDa
    Gene ID
    3553
    HGNC
    3553
    Pathways
    NF-kappaB Signaling, Interferon-gamma Pathway, TLR Signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
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